Proteomic analysis of exosomes isolated from human malignant pleural effusions

…, JP van Meerbeeck, SA Burgers… - American journal of …, 2004 - atsjournals.org
Exosomes are membrane vesicles from endosomal origin secreted by various cells such as
hematopoietic, epithelial, and tumor cells. Exosomes secreted by tumor cells contain specific …

[HTML][HTML] Nivolumab plus ipilimumab in lung cancer with a high tumor mutational burden

…, E Minenza, H Linardou, S Burgers… - … England Journal of …, 2018 - Mass Medical Soc
Background Nivolumab plus ipilimumab showed promising efficacy for the treatment of non–small-cell
lung cancer (NSCLC) in a phase 1 trial, and tumor mutational burden has …

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy

S Leijen, SA Burgers, P Baas, D Pluim, M Tibben… - Investigational new …, 2015 - Springer
Background This phase I/II study determined the maximal tolerable dose, dose limiting
toxicities, antitumor activity, the pharmacokinetics and pharmacodynamics of ruthenium …

Proteomic analysis of exosomes secreted by human mesothelioma cells

…, MJ Kleijmeer, JB Prins, L Zitvogel, SA Burgers… - The American journal of …, 2004 - Elsevier
Exosomes are small membrane vesicles secreted into the extracellular compartment by
exocytosis. Tumor exosomes may be involved in the sampling of antigens to antigen presenting …

[HTML][HTML] Programmed death 1 blockade with nivolumab in patients with recurrent malignant pleural mesothelioma

…, H Klomp, K Hartemink, S Burgers… - Journal of Thoracic …, 2018 - Elsevier
Introduction Malignant pleural mesothelioma (MPM) has limited treatment options and a poor
outcome. Programmed death 1/programmed death ligand 1 (PD-L1) checkpoint inhibitors …

Ipilimumab and nivolumab in the treatment of recurrent malignant pleural mesothelioma (INITIATE): results of a prospective, single-arm, phase 2 trial

…, V van der Noort, E Harms, S Burgers… - The Lancet …, 2019 - thelancet.com
Background Single-drug checkpoint inhibition has shown efficacy in patients with recurrent
malignant pleural mesothelioma. Here, we assessed the safety and efficacy of the …

[PDF][PDF] Randomized phase II and pharmacogenetic study of pemetrexed compared with pemetrexed plus carboplatin in pretreated patients with advanced non-small …

EF Smit, SA Burgers, B Biesma, HJ Smit, P Eppinga… - J Clin Oncol, 2009 - academia.edu
Burgers, Bonne Biesma, Hans JM Smit, Pier Eppinga, Anne-Marie C. Dingemans,
Markus Joerger, Jan H. Schellens, Andrew Vincent, Nico van Zandwijk, and Harry JM Groen …

In vivo measurement of the local optical properties of tissue by use of differential path-length spectroscopy

A Amelink, HJCM Sterenborg, MPL Bard, SA Burgers - Optics letters, 2004 - opg.optica.org
We demonstrate the capability of differential path-length spectroscopy (DPS) to determine
the local optical properties of tissue in vivo. DPS measurements on bronchial mucosa are …

An immune response enriched 72-gene prognostic profile for early-stage non–small-cell lung cancer

…, AT Witteveen, W Rzyman, A Floore, S Burgers… - Clinical cancer …, 2009 - AACR
Purpose: Current staging methods are imprecise for predicting prognosis of early-stage non–small-cell
lung cancer (NSCLC). We aimed to develop a gene expression profile for stage I …

Pulmonary function changes after radiotherapy in non–small-cell lung cancer patients with long-term disease-free survival

…, K De Jaeger, JSA Belderbos, SA Burgers… - International Journal of …, 2005 - Elsevier
Purpose: To evaluate the changes in pulmonary function after high-dose radiotherapy (RT)
for non-small-cell lung cancer in patients with a long-term disease-free survival. Methods and …