Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

…, S Mead, TH Mosley Jr, DA Bennett, TB Harris… - Nature …, 2013 - nature.com
Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous
studies; however, a large portion of the genetic risk for this disease remains unexplained. …

Biological, clinical and population relevance of 95 loci for blood lipids

…, C Hayward, AS Havulinna, ND Hastie, TB Harris… - Nature, 2010 - nature.com
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density
lipoprotein cholesterol and triglycerides are among the most important risk factors for …

The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study

BH Goodpaster, SW Park, TB Harris… - The Journals of …, 2006 - academic.oup.com
Background. The loss of muscle mass is considered to be a major determinant of strength
loss in aging. However, large-scale longitudinal studies examining the association between …

Elevated C-reactive protein levels in overweight and obese adults

…, LM Bouter, GM McQuillan, MH Wener, TB Harris - Jama, 1999 - jamanetwork.com
ContextHuman adipose tissue expresses and releases the proinflammatory cytokine interleukin
6, potentially inducing low-grade systemic inflammation in persons with excess body fat.…

[HTML][HTML] Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old

KF Adams, A Schatzkin, TB Harris… - … England Journal of …, 2006 - Mass Medical Soc
Background Obesity, defined by a body-mass index (BMI) (the weight in kilograms divided
by the square of the height in meters) of 30.0 or more, is associated with an increased risk of …

The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates

…, PM Cawthon, RR McLean, TB Harris… - … Series A: Biomedical …, 2014 - academic.oup.com
Background. Low muscle mass and weakness are common and potentially disabling in
older adults, but in order to become recognized as a clinical condition, criteria for diagnosis …

Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort

…, FA Tylavsky, SM Rubin, TB Harris - The Journals of …, 2006 - academic.oup.com
Background. Although muscle strength and mass are highly correlated, the relationship
between direct measures of low muscle mass (sarcopenia) and strength in association with …

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

…, BM Psaty, M Lorentzon, T Foroud, TB Harris… - The Lancet, 2010 - thelancet.com
Background Vitamin D is crucial for maintenance of musculoskeletal health, and might also
have a role in extraskeletal tissues. Determinants of circulating 25-hydroxyvitamin D …

Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly

TB Harris, L Ferrucci, RP Tracy, MC Corti… - The American journal of …, 1999 - Elsevier
PURPOSE: To investigate whether interleukin-6 and C-reactive protein levels predict all-cause
and cause-specific mortality in a population-based sample of nondisabled older people. …

Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons

…, SM Rubin, EM Simonsick, TB Harris - The Journals of …, 2005 - academic.oup.com
Background. Lower muscle mass has been correlated with poor physical function; however,
no studies have examined this relationship prospectively. This study aims to investigate …