Idiopathic pulmonary fibrosis is a fatal lung disease characterized by progressive and
excessive accumulation of myofibroblasts and in the lung. Connective-tissue growth factor (CTGF) …

The thymus has spatially distinct microenvironments, the cortex and the medulla, where the
developing T-cells are selected to mature or die through the interaction with thymic stromal …

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with an unknown cause. Two
drugs, nintedanib and pirfenidone, have been shown to slow, but not stop, disease progression…

Idiopathic pulmonary fibrosis is a fatal age-related lung disease characterised by progressive
and irreversible scarring of the lung. Although the details are not fully understood, there …

Idiopathic pulmonary fibrosis (IPF) is a progressive disease of the lung parenchyma, causing
significant morbidity through worsening dyspnoea and overall functional decline. IPF is …

Background The role of mast cells accumulating in idiopathic pulmonary fibrosis (IPF) lungs
is unknown. Objectives We investigated the effect of fibrotic extracellular matrix (ECM) on …

Neutrophils are highly motile leukocytes that play important roles in the innate immune
response to invading pathogens. Neutrophils rapidly migrate to the site of infections and kill …

Introduction Pulmonary fibrosis includes several lung disorders characterized by progressive
fibrosis, of which idiopathic pulmonary fibrosis (IPF) is a particularly severe form with a …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease characterized by
progressive lung scarring. IPF-related pulmonary vascular remodeling and pulmonary …

Immune cells have been implicated in interstitial lung diseases (ILDs), although their phenotypes
and effector mechanisms remain poorly understood. To better understand these cells, …