Superparamagnetic graphene oxide–Fe 3 O 4 nanoparticles hybrid for controlled targeted drug carriers

X Yang, X Zhang, Y Ma, Y Huang, Y Wang… - Journal of materials …, 2009 - pubs.rsc.org
A superparamagnetic graphene oxide –Fe3O4nanoparticles hybrid (GO–Fe3O4) was
prepared via a simple and effective chemical precipitation method. The amount of loading of …

An Intelligent Biomimetic Nanoplatform for Holistic Treatment of Metastatic Triple-Negative Breast Cancer via Photothermal Ablation and Immune Remodeling

Y Cheng, Q Chen, Z Guo, M Li, X Yang, G Wan… - ACS …, 2020 - ACS Publications
Metastasis is one of the main causes of failure in the treatment of triple-negative breast
cancer (TNBC). Immunotherapy brings hope and opportunity to solve this challenge, while its …

Cardiovascular event prediction by machine learning: the multi-ethnic study of atherosclerosis

B Ambale-Venkatesh, X Yang, CO Wu, K Liu… - Circulation …, 2017 - Am Heart Assoc
Rationale: Machine learning may be useful to characterize cardiovascular risk, predict
outcomes, and identify biomarkers in population studies. Objective: To test the ability of random …

Delivery of telomerase reverse transcriptase small interfering RNA in complex with positively charged single-walled carbon nanotubes suppresses tumor growth

Z Zhang, X Yang, Y Zhang, B Zeng, S Wang, T Zhu… - Clinical cancer …, 2006 - AACR
Purpose: To determine whether -CONH-(CH 2 ) 6 -NH 3 + Cl − functionalized single-walled
carbon nanotubes (SWNT) carrying complexed small interfering RNA (siRNA) can enter into …

High-efficiency loading and controlled release of doxorubicin hydrochloride on graphene oxide

X Yang, X Zhang, Z Liu, Y Ma, Y Huang… - The Journal of Physical …, 2008 - ACS Publications
A novel graphene oxide−doxorubicin hydrochloride nanohybrid (GO−DXR) was prepared via
a simple noncovalent method, and the loading and release behaviors of DXR on GO were …

Multi-functionalized graphene oxide based anticancer drug-carrier with dual-targeting function and pH-sensitivity

X Yang, Y Wang, X Huang, Y Ma, Y Huang… - Journal of materials …, 2011 - pubs.rsc.org
A dual-targeting drug delivery and pH-sensitive controlled release system based on multi-functionalized
graphene oxide (GO) was established in order to enhance the effect of targeted …

B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo

Y Li, G Toraldo, A Li, X Yang, H Zhang, WP Qian… - Blood, 2007 - ashpublications.org
Bone homeostasis is regulated by a delicate balance between osteoblastic bone formation
and osteoclastic bone resorption. Osteoclastogenesis is controlled by the ratio of receptor …

[HTML][HTML] IFN-γ stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation

…, MR Ryan, M Terauchi, K Page, X Yang… - The Journal of …, 2007 - Am Soc Clin Investig
T cell–produced cytokines play a pivotal role in the bone loss caused by inflammation,
infection, and estrogen deficiency. IFN-γ is a major product of activated T helper cells that can …

Tiragolumab plus atezolizumab versus placebo plus atezolizumab as a first-line treatment for PD-L1-selected non-small-cell lung cancer (CITYSCAPE): primary and …

…, KH Lee, B Massuti, S Hiret, JCH Yang… - The Lancet …, 2022 - thelancet.com
Background Targeted inhibition of the PD-L1–PD-1 pathway might be further amplified
through combination of PD-1 or PD-L1 inhibitors with novel anti-TIGIT inhibitory immune …

[HTML][HTML] Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial

…, GL Chupp, DS Cheung, W Theess, X Yang… - Journal of allergy and …, 2021 - Elsevier
Background The IL-33/ST2 pathway is linked with asthma susceptibility. Inhaled allergens,
pollutants, and respiratory viruses, which trigger asthma exacerbations, induce release of IL-…