Differences in airway cytokine profile in severe asthma compared to moderate asthma

J Shannon, P Ernst, Y Yamauchi, R Olivenstein… - Chest, 2008 - Elsevier
Background Some studies of severe asthma suggest that persistence or alteration in the
pattern of inflammation may be associated with the severity of the disease. Whether there are …

Airway inflammation assessed by invasive and noninvasive means in severe asthma: eosinophilic and noneosinophilic phenotypes

C Lemière, P Ernst, R Olivenstein, Y Yamauchi… - Journal of Allergy and …, 2006 - Elsevier
BACKGROUND: Airway inflammation assessed by bronchial biopsies demonstrates distinct
eosinophilic and noneosinophilic phenotypes in severe asthma, but their relationship to …

[HTML][HTML] The Multicopy Gene Sly Represses the Sex Chromosomes in the Male Mouse Germline after Meiosis

J Cocquet, PJI Ellis, Y Yamauchi, SK Mahadevaiah… - PLoS …, 2009 - journals.plos.org
Studies of mice with Y chromosome long arm deficiencies suggest that the male-specific
region (MSYq) encodes information required for sperm differentiation and postmeiotic sex …

Effect of salmeterol/fluticasone propionate on airway inflammation in COPD: a randomised controlled trial

…, P Christodoulopoulos, F Maltais, Y Yamauchi… - Thorax, 2007 - thorax.bmj.com
Background: Airway inflammation in chronic obstructive pulmonary disease (COPD) is
characterised by infiltration of CD8+ T cells and CD68+ macrophages and an increased number …

[HTML][HTML] Mouse zygotes respond to severe sperm DNA damage by delaying paternal DNA replication and embryonic development

JE Gawecka, J Marh, M Ortega, Y Yamauchi… - PLoS …, 2013 - journals.plos.org
Mouse zygotes do not activate apoptosis in response to DNA damage. We previously reported
a unique form of inducible sperm DNA damage termed sperm chromatin fragmentation (…

[HTML][HTML] TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts

…, K Makita, N Miyashita, A Mitani, T Jo, Y Yamauchi… - Scientific reports, 2017 - nature.com
Transcriptional coactivator with PDZ-binding motif (TAZ) regulates a variety of biological
processes. Nuclear translocation and activation of TAZ are regulated by multiple mechanisms, …

Paradoxical association between body mass index and in-hospital mortality in elderly patients with chronic obstructive pulmonary disease in Japan

Y Yamauchi, W Hasegawa, H Yasunaga… - … journal of chronic …, 2014 - Taylor & Francis
Background and objective The prevalence and mortality of chronic obstructive pulmonary
disease (COPD) in elderly patients are increasing worldwide. Low body mass index (BMI) is a …

Sperm chromatin remodeling after intracytoplasmic sperm injection differs from that of in vitro fertilization

A Ajduk, Y Yamauchi, MA Ward - Biology of reproduction, 2006 - academic.oup.com
Intracytoplasmic sperm injection (ICSI) is a popular method used in assisted conception, and
live offspring have been born from a variety of species, including humans. In ICSI, sperm …

Two Y genes can replace the entire Y chromosome for assisted reproduction in the mouse

Y Yamauchi, JM Riel, Z Stoytcheva, MA Ward - Science, 2014 - science.org
The Y chromosome is thought to be important for male reproduction. We have previously
shown that, with the use of assisted reproduction, live offspring can be obtained from mice …

Simultaneous stimulation with TGF-β1 and TNF-α induces epithelial mesenchymal transition in bronchial epithelial cells

S Kamitani, Y Yamauchi, S Kawasaki… - International archives of …, 2011 - karger.com
Background: Airway remodeling is an important feature of chronic airway disease, but the
mechanisms involved remain unclear. Recently, epithelial mesenchymal transition (EMT) was …