[HTML][HTML] AMPK activation by ASP4132 inhibits non-small cell lung cancer cell growth

Y Xia, J Zha, YH Sang, H Yin, G Xu, J Zhen… - Cell Death & …, 2021 - nature.com
Activation of adenosine monophosphate-activated protein kinase (AMPK) is able to produce
significant anti-non-small cell lung cancer (NSCLC) cell activity. ASP4132 is an orally active …

[HTML][HTML] The anti-non-small cell lung cancer cell activity by a mTOR kinase inhibitor PQR620

JH Zha, YC Xia, CL Ye, Z Hu, Q Zhang, H Xiao… - Frontiers in …, 2021 - frontiersin.org
In non-small-cell lung carcinoma (NSCLC), aberrant activation of mammalian target of
rapamycin (mTOR) contributes to tumorigenesis and cancer progression. PQR620 is a novel and …

[HTML][HTML] Profile of clinical and analytical parameters in bronchiectasis patients during the COVID-19 pandemic: a one-year follow-up pilot study

L Qin, F Gonçalves-Carvalho, Y Xia, J Zha… - Journal of clinical …, 2022 - mdpi.com
Whether the COVID-19 pandemic may have modified the clinical planning and course in
bronchiectasis patients remains to be fully elucidated. We hypothesized that the COVID-19 …

RETRACTED: Resibufogenin suppresses growth and metastasis through inducing caspase‐1‐dependent pyroptosis via ROS‐mediated NF‐κB suppression in non …

…, YG Liu, F Li, LQ Wang, JH Zha, YC Xia… - The Anatomical …, 2021 - Wiley Online Library
The purpose of this study is to explore the antitumor properties of resibufogenin (RB) in non‐small
cell lung cancer (NSCLC) and elucidate its underlying mechanism. A549 and H520 …

[HTML][HTML] Respiratory and peripheral muscle weakness and body composition abnormalities in non-cystic fibrosis bronchiectasis patients: gender differences

…, A Balaña-Corberó, J Martínez-Llorens, L Qin, Y Xia… - Biomedicines, 2022 - mdpi.com
As demonstrated in COPD, bronchiectasis patients may experience respiratory and peripheral
muscle dysfunction. We hypothesized that respiratory and peripheral (upper and lower …

[HTML][HTML] Do redox balance and inflammatory events take place in mild bronchiectasis? a hint to clinical implications

…, S Esteban-Cucó, JM Maiques, Y Xia… - Journal of clinical …, 2021 - mdpi.com
We hypothesized that in mild bronchiectasis patients, increased systemic inflammation and
redox imbalance may take place and correlate with clinical parameters. In plasma samples …

[HTML][HTML] JAK2 inhibitor TG101348 overcomes erlotinib-resistance in non-small cell lung carcinoma cells with mutated EGF receptor

F Zhang, W Yang, S Duan, Y Xia, R Zhu, Y Chen - Oncotarget, 2015 - ncbi.nlm.nih.gov
Non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR)
mutations are responsive to EGFR-tyrosine kinase inhibitor (EGFR-TKI). However, NSCLC …

Gene expression profile of epithelial–mesenchymal transition in tumours of patients with nonsmall cell lung cancer: the influence of COPD

Y Xia, J Zha, V Curull, A Sánchez-Font… - ERJ Open …, 2022 - Eur Respiratory Soc
Epithelial–mesenchymal transition (EMT) is involved in the pathophysiology of lung cancer (LC)
and COPD, and the latter is an important risk factor for LC. We hypothesised that the …

Experimental study on inhibition effects of the XAF1 gene against lung cancer cell proliferation

WT Yang, DL Chen, FQ Zhang, YC Xia… - Asian Pacific Journal …, 2014 - koreascience.kr
Objective: To investigate the effect of high expression of XAF1 in vivo or in vitro on lung
cancer cell growth and apoptosis. Methods: 1. The A549 human lung cancer cell line was …

Constructing built-in electric field via CuO/NiO heterojunction for electrocatalytic reduction of nitrate at low concentrations to ammonia

Y Chen, X Xia, L Tian, M Yin, LL Zheng, Q Fu… - Chinese Chemical …, 2024 - Elsevier
Electrocatalytic reduction of nitrate (NO 3 − ) at low concentrations to ammonia (NH 4 + ) still
faces challenges of low NO 3 − conversion and NH 4 + selectivity due to the sluggish mass …