Reliability of maximum oxygen uptake in cardiopulmonary exercise testing with continuous laryngoscopy
- Mette Engan1,2,6⇑,
- Ida Jansrud Hammer1,6,
- Marianne Bekken2,
- Thomas Halvorsen1,2,3,
- Zoe Louise Fretheim-Kelly2,4,
- Maria Vollsæter1,2,
- Lars Peder Vatshelle Bovim5,
- Ola Drange Røksund1,5 and
- Hege Clemm1,2
- 1Department of Pediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway
- 2Department of Clinical Science, University of Bergen, Norway
- 3Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway
- 4Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway
- 5Faculty of Health and Social Sciences, Western Norway University of Applied Sciences
- 6Contributed equally as co-first authors
- Mette Engan, Department of Pediatric and Adolescent Medicine, Haukeland University Hospital, Jonas Lies vei 65, N-5021 Bergen, Norway. E-mail: metteengan{at}hotmail.com
Abstract
Objective Cardiopulmonary exercise test (CPET) is the gold standard to evaluate symptom-limiting exercise intolerance, while continuous laryngoscopy performed during exercise (CLE) is required to diagnose exercised induced laryngeal obstruction (EILO). Combining CPET with CLE would save time and resources; however, the CPET data may be distorted by the extra equipment. We therefore aimed to study if CPET with CLE influences peak oxygen uptake (VO2peak) and other gas exchange parameters when compared to a regular CPET.
Methods Forty healthy athletes without exercise related breathing problems, 15–35 years of age, performed CPET to peak exercise with and without an added CLE set-up, in randomised order 2–3 days apart, applying an identical computerised treadmill protocol.
Results At peak exercise, the mean difference (95% confidence interval) between CPET with and without extra CLE set-up for VO2peak, respiratory exchange ratio (RER), minute ventilation (VE) and heart rate (HR) was 0.2 (−0.4 to 0.8) mL·kg−1·min−1, 0.01(−0.007 to 0.027) units, 2.6 (−1.3 to 6.5) L·min−1, and 1.4 (−0.8 to 3.5) beats/minute, respectively. Agreement (95% limits of agreement) for VO2peak, RER and VE was 0.2 (±3.7) mL·kg−1·min−1, 0.01 (±0.10) units and 2.6 (±24.0) L·min−1, respectively. No systematic or proportional bias was found except for the completed distance, which was 49 (95% CI 16 to 82) meters longer during CPET.
Conclusions Parameters of gas exchange including VO2peak and RER, obtained from a maximal CPET performed with the extra CLE set-up, can be used interchangeably with data obtained from standard CPET, thus preventing unnecessary additional testing.
Footnotes
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Conflict of interest: Dr. Engan has nothing to disclose.
Conflict of interest: Dr. Hammer has nothing to disclose.
Conflict of interest: Marianne Bekken has nothing to disclose.
Conflict of interest: Dr. Halvorsen has nothing to disclose.
Conflict of interest: Zoe Fretheim-Kelly has nothing to disclose.
Conflict of interest: Dr. Vollsæter has nothing to disclose.
Conflict of interest: Dr. Bovim has nothing to disclose.
Conflict of interest: Dr. Røksund has nothing to disclose.
Conflict of interest: Dr. Clemm has nothing to disclose.
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- Received November 4, 2020.
- Accepted November 25, 2020.
- Copyright ©ERS 2020
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